Jeong Doo Heo Selected Research

Neoplasms (Cancer)

7/2022	Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects.
8/2021	Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-κB Signaling through PTEN Activation in Hepatocellular Carcinoma.
1/2021	Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer.
1/2020	Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells.
12/2018	Identification of a novel biomarker in tangeretin‑induced cell death in AGS human gastric cancer cells.
10/2018	Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin.
8/2018	Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway.
1/2018	Inhibition of IAP's and activation of p53 leads to caspase-dependent apoptosis in gastric cancer cells treated with Scutellarein.
1/2018	Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia.
9/2015	Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand.

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Jeong Doo Heo Research Topics

Disease

11	Neoplasms (Cancer) 07/2022 - 09/2015
8	Stomach Neoplasms (Stomach Cancer) 04/2021 - 09/2015
7	Inflammation (Inflammations) 06/2022 - 09/2016
3	Neoplasm Metastasis (Metastasis) 08/2021 - 02/2017
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 06/2020 - 01/2018
3	AIDS-Related Complex (ARC) 12/2013 - 09/2007
2	Hepatocellular Carcinoma (Hepatoma) 08/2021 - 02/2017
2	Adenocarcinoma 07/2017 - 09/2015
1	Colonic Neoplasms (Colon Cancer) 07/2022
1	COVID-19 06/2022
1	Sarcopenia 03/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2021
1	Thyroid Neoplasms (Thyroid Cancer) 01/2021
1	Leukemia 06/2020
1	Pneumonia (Pneumonitis) 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 07/2017
1	Lymphoma (Lymphomas) 04/2017
1	Wounds and Injuries (Trauma) 02/2017
1	Alzheimer Disease (Alzheimer's Disease) 09/2016
1	Hepatoblastoma 12/2015
1	Carcinoma (Carcinomatosis) 09/2015
1	Atopic Dermatitis (Atopic Eczema) 01/2015
1	Dermatitis 01/2015

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 07/2022 - 02/2017
7	FlavonoidsIBA 01/2020 - 12/2015
4	scutellareinIBA 06/2022 - 01/2018
3	Biological ProductsIBA 08/2021 - 09/2015
3	Biomarkers (Surrogate Marker)IBA 03/2021 - 12/2018
3	Pharmaceutical PreparationsIBA 03/2021 - 11/2019
3	MetalsIBA 12/2013 - 09/2007
3	Stainless Steel (Steel, Stainless)IBA 12/2013 - 09/2007
2	Phosphotransferases (Kinase)IBA 07/2022 - 01/2021
2	CytokinesIBA 06/2022 - 01/2015
2	flavoneIBA 08/2021 - 01/2020
2	tyrosine receptor (receptor, tyrosine)IBA 06/2020 - 01/2018
2	pectolinarigeninIBA 10/2018 - 08/2018
2	CaspasesIBA 01/2018 - 04/2017
1	KRC-108IBA 07/2022
1	Phospholipases (Phospholipase)IBA 07/2022
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 06/2022
1	Mitogen-Activated Protein KinasesIBA 06/2022
1	LipopolysaccharidesIBA 06/2022
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2022
1	EndotoxinsIBA 06/2022
1	Peptides (Polypeptides)IBA 10/2020
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2020
1	fms-Like Tyrosine Kinase 3IBA 05/2019
1	Ligases (Synthetase)IBA 01/2019
1	Volatile Oils (Essential Oils)IBA 01/2019
1	Terpenes (Terpenoids)IBA 01/2019
1	UbiquitinIBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2019
1	tangeretinIBA 12/2018
1	Cytotoxins (Cytolysins)IBA 01/2018
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 04/2017
1	IgA receptor (protein B)IBA 04/2017
1	Matrix Metalloproteinases (MMPs)IBA 02/2017
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 02/2017
1	Ergocalciferols (Ergocalciferol)FDA LinkGeneric 09/2016
1	GlycosidesIBA 09/2015
1	flavanoneIBA 09/2015
1	poncirinIBA 09/2015
1	AntioxidantsIBA 09/2015
1	Fas Ligand Protein (Fas Ligand)IBA 09/2015
1	naringinIBA 09/2015
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2015
1	Immunoglobulin E (IgE)IBA 01/2015
1	Polysaccharides (Glycans)IBA 01/2015

Therapy/Procedure

4	Therapeutics 08/2021 - 01/2018
1	Aftercare (After-Treatment) 08/2021
1	Oral Administration 01/2021
1	Intravenous Administration 01/2018